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'Overdose drug' hope for diabetes sufferers



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Published Date: 29 January 2008
A DRUG used to reverse the effects of paracetamol overdoses might prove a lifesaver for diabetes sufferers.
NHS-funded work has found that N-acetylcysteine can be used to control "sticky" blood, which is common in patients with diabetes and can lead to blood clots, heart attacks, strokes and blocked arteries in the legs.

Results of the research in the
Highlands have been so promising that Scottish Health Innovations, a Glasgow-based development company, is to fund a patent application and the next level of testing.

More than 2.3 million people in the UK have been diagnosed with diabetes, while another 750,000 are thought to be sufferers but do not know it. Scotland has more than 200,000 people with diabetes. In NHS Highland's area alone, the number is more than 11,000, and that is forecast to rise to 13,000 by 2017.

About 80 per cent of diabetes sufferers die from heart-related problems and the condition raises by fifteen times the likelihood of leg amputation as a result of blocked arteries.

The research was carried out in Inverness by Kyle Gibson, 21, a medical student at the department of diabetes, part of the UHI Millennium Institute, the body hoping to become the university of the Highlands and Islands.



The full article contains 219 words and appears in The Scotsman newspaper.
Page 1 of 1

  • Last Updated: 28 January 2008 9:54 PM
  • Source: The Scotsman
  • Location: Edinburgh
 
1

Douglas,

Bathgate 29/01/2008 00:19:11
If it all pans out, Kyle Gibson may be a hero of the 21st century.
Thank you young man.
2

Dr Philip Rossiter,

Sydney 29/01/2008 04:54:33
The compound resveratrol has shown interesting neuroprotective properties in clinical trials. Drs. Anderson and Setia reported in a January paper that of 121 with memory loss and early Alzheimers symptoms patients given biotivia Transmax, an extract of red wine used by researchers, 94 showed marked improvement in cholesterol levels, reduced inflammation and improved circulation. Resveratrol works by activating the human Sirt 1,2,3 genes much like caloric restriction does. Sirtris pharma is developing a synthetic version of transmax which it intends to have on the market in five years. In another study by Dr. Sinclair of Harvard published in the journal Nature in November transmax was shown to increase the life span of obese mammals by 31%. This is an exciting area of research and could lead to some extraordinary new preventative strategies and safer, less invasive treatments for a number of diseases. I Dr. Sinclair's study of obese mice he found that those fed resveratrol lived 31% longer and were free of cardiovascular diseases.

 

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