'Addict' hitch for nicotine drugs
Published Date:
14 July 2008
By John von Radowitz
NICOTINE'S addictive properties are closely tied to its ability to improve memory and learning, new research has shown.
The findings present an obstacle to using the tobacco chemical to treat conditions such as Alzheimer's disease.
Previous research has shown nicotine boosts memory and alertness, but nicotine is difficult to administer other than by smoking, and is highly addictive.
Pharmaceutical companies are keen to develop safe nicotine-like substances for Alzheimer's and other forms of dementia.
The new research presented today at FENS 2008, the Forum of European Neuroscience meeting in Geneva, Switzerland, shows why this goal is so elusive.
Scientists led by Professor Ian Stolerman, from the Institute of Psychiatry at King's College London, studied the underlying mechanisms behind nicotine's effects on the brain.
Prof Stolerman said:
"The cognitive 'boost' that many smokers experience from nicotine probably contributes to the reason people smoke cigarettes, so it may not be possible to totally prevent addiction.
"Nevertheless, the potential for abuse of a medicine based on a pure nicotine-like substance is likely to be very small."
The full article contains 180 words and appears in The Scotsman newspaper.
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Last Updated:
13 July 2008 6:40 PM
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Source:
The Scotsman
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Location:
Edinburgh