IN THE depths of the Antarctic winter, researchers at Australia's research bases might as well be on the moon. Or on their way to Mars.
"When you are in Antarctica you know you can't get out – there's no rescue during winter. And that changes one's mentality," said Des Lugg, head of polar medicine at the Australian Antarctic Division from 1968-2001 and now a consultant to Nasa.
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You can get back faster from the International Space Station than you can from the Antarctic in the depths of winter," he said.
It's that very isolation that makes Australia's Antarctic bases and their expeditions perfect for planning long-term space missions, he said.
Since 1993, Nasa has run a joint programme with the Australian Antarctic Division (AAD) studying human health and how small groups adapt to many months of isolation working in the coldest place on Earth.
"Australia's Antarctic programme has some of the most isolated stations in Antarctica where we have total isolation for up to nine months of the year," said Jeff Ayton, the division's chief medical officer.
He said Australia's Antarctic stations were good analogues for space travel and figuring out how people get along in close environments.
"It's an extreme environment and we've got real people in real hazardous situations, and their survival is dependent on technology and complex systems not too dissimilar to survival in space.
"We also have wide experience of the medical conditions that can occur in Antarctic stations and they are of interest to people planning for long-term missions to Mars and other exploratory missions," Ayton added.
In particular, Nasa has shown interest in the division's decades-old experience in using super-generalist doctors at its bases. Some of these have been recruited from rural Australia, home of traditional country doctors who are adept at tackling just about any medical challenge.
Doctors on the frozen continent have confronted such wide-ranging problems as brain surgery, fractures and mental health problems.
"We have managed pregnancies in Antarctica. That is part of the medical spectrum we have to deal with," Ayton said.
Such broad experience would be crucial on a long-term mission to Mars or beyond.
Other medical conditions also present challenges. Studies have shown Antarctic researchers suffer vitamin D deficiencies through lack of sunlight, leading to depression, as well as weaker immune systems.
Ayton said studies have shown the reactivation of latent viruses, such as the Epstein-Barr virus or other members of the herpes virus family.
"It's not fully known to date what causes immune suppression. We've looked at psychological factors on the immune system. We've looked at vitamin D effects on the immune system and the stresses in small, confined environments," he said, adding that studies have shown similar changes to the immune system in space.
Lugg said viruses tend to lie dormant in the body and reactivate in space or in Antarctica.
"No one has exhibited any clinical disease. This is the other interesting thing. Although they have altered their immune status, there is no clinical disease that we've been able to detect in Antarctica to show for the altered immune response," he said.
Mental health is another top issue. Being confined to a small base with a dozen or so colleagues for months away from family and friends can be a major source of stress for some expedition members.
Lugg and Ayton said most people adapted well to life in Antarctica, with only rare cases of mental breakdowns.
Lugg did a 25-year study of documented behavioural health problems in Antarctica and said the incidence rate was 4% of all primary consultations to the base doctor.
"You have sleep problems, but what you are looking for are the classic psychosis episodes," Lugg said.
"There was a guy one year who heard babies cry. He came to the doctor and he said: 'I'm hearing voices.' Fortunately, he was able to be got out because it was just before the close of winter."
While such cases were rare, having just one episode in Antarctica or in space could be disastrous.
"However many you have going to Mars in a tin can, if someone has a major psychotic event they are going to have great difficulty handling that."
Pre-expedition health and psychological screening, and possibly genetic testing in the future, were crucial.
"We don't take asthmatics, you don't take anyone who's epileptic, who's on cardiac medication or had a cardiac problem, hypertension – you screen out a vast number of people," said Lugg, who spent five years working in Washington with Nasa's Office of the Chief Health and Medical Officer until 2006.
Also crucial were the "niceties", said Lugg, such as understanding human nature, as well as cultural differences.
"When you are dealing with humans, you've got to get back to the very basics, and that is their ability to live together, to work together and the health side of it".
This included fighting boredom on bases by providing a good variety of food.
It also meant understanding that sex, and a glass or two of wine with dinner, were normal desires.
Ayton said there were no restrictions on explorers when it came to sex.
Whatever amorous liaisons occurred between researchers were their own business during the nine months or more away from families.
The full article contains 893 words and appears in Scotland On Sunday newspaper.
